Knowledge and Understanding of the Safety and Efficacy Aspects of BRIDION® Among Canadian Anesthesiologists

Autor: Annette Stemhagen, Parambir Bhangu, Wenjun Zhong, Michele Julian, Gretty Deutsch, Carol Koro
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Drugs - Real World Outcomes, Vol 7, Iss 3, Pp 251-256 (2020)
Druh dokumentu: article
ISSN: 2199-1154
2198-9788
DOI: 10.1007/s40801-020-00200-z
Popis: Abstract Background BRIDION® (sugammadex sodium) is an agent for the reversal of neuromuscular blockade (NMB) induced by rocuronium and vecuronium in general anesthesia. Following the approval of sugammadex in Canada (February 2016), Health Canada required a survey to assess the knowledge and understanding of the safety and efficacy aspects of sugammadex among anesthesiologists in Canada. Objective Our objective was to evaluate how well the anesthesiologists in Canada understood the safety and efficacy aspects of sugammadex. Methods A survey was implemented among anesthesiologists in Canada via internet/phone. The survey was organized to test the knowledge of anesthesiologists by utilizing 11 key questions regarding the safety and efficacy of sugammadex. Five additional safety questions that were not considered part of the key messages but were important concepts for anesthesiologists to know when administering sugammadex were also included. Results A total of 202 completed surveys were collected. Based on an a priori threshold of understanding of 75%, 9 out of 11 key messages scored at or above this threshold. The two messages that scored below this threshold involved (1) knowledge that sugammadex is not indicated for use in children aged
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