Sometimes Treatment Kills: Ceftriaxone-induced Hemolytic Anemia in a Case of Pyogenic Meningitis

Autor: Akshaya Tomar, Somasundaram Venkatesan, Swaraj P. Khajuria
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Medical Journal of Dr. D.Y. Patil Vidyapeeth, Vol 17, Iss 2, Pp 465-467 (2024)
Druh dokumentu: article
ISSN: 2589-8302
2589-8310
DOI: 10.4103/mjdrdypu.mjdrdypu_313_23
Popis: Drug-induced immune hemolytic anemia (DIIHA) is a rare condition that is often misdiagnosed or not diagnosed promptly, even at specialized medical facilities. The leading causes of DIIHA are antibiotics, particularly second and third-generation cephalosporins, and platinum-based chemotherapy. While identifying the responsible drug and discontinuing it typically resolves the issue, fatalities may still occur in cases of progressive immune-mediated hemolysis and underlying medical conditions. This case involves an 80-year-old man receiving injectable broad-spectrum antibiotics, including ceftriaxone, for pyogenic meningitis, who experienced severe hemolytic anemia that ultimately led to intracranial hemorrhage and death.
Databáze: Directory of Open Access Journals