| Autor: |
Myriam Amsallem, Ryan J. Tedford, Andre Denault, Andrew J. Sweatt, Julien Guihaire, Kristofer Hedman, Shadi Peighambari, Juyong Brian Kim, Xiao Li, Robert J. H. Miller, Olaf Mercier, Elie Fadel, Roham Zamanian, Francois Haddad |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 11 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2047-9980 |
| DOI: |
10.1161/JAHA.119.016265 |
| Popis: |
Background The strong linear relation between mean (MPAP) and systolic (SPAP) pulmonary arterial pressure (eg, SPAP=1.62×MPAP) has been mainly reported in precapillary pulmonary hypertension. This study sought to quantify the influence of pulmonary arterial wedge pressure (PAWP), heart rate, and age on the MPAP‐SPAP relation. Methods and Results An allometric equation relating invasive MPAP and SPAP was developed in 1135 patients with pulmonary arterial hypertension, advanced lung disease, chronic thromboembolic pulmonary hypertension, or left heart failure. The equation was validated in 60 885 patients from the United Network for Organ Sharing (UNOS) database referred for heart and/or lung transplant. The MPAP/SPAP longitudinal stability was assessed in pulmonary arterial hypertension with repeated right heart catheterization. The equation obtained was SPAP=1.39×MPAP×PAWP−0.07×(60/heart rate)0.12×age0.08 (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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