| Autor: |
Mungli Prakash, Vivekananda Kedage, Manjunatha S Muttigi, Nataraj K, Waqas Wahid Baig, Ravindra Prabhu Attur |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Online Journal of Health & Allied Sciences, Vol 9, Iss 2 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
0972-5997 |
| Popis: |
Introduction: Tubular damage is common finding in acute renal failure (ARF). Various etiologies have been put forth to explain the tubular damage in ARF, one important mechanism among them is oxidative damage to renal tubules. Several biomolecules including low-molecular weight peptides and enzymes in urine have been proposed as early markers of renal failure. Current study has been undertaken to study the thiol stress and glutathione-S-transferase (GST) levels in ARF patients. Method: 58 ARF patients and 55 healthy controls were selected based on inclusion and exclusion criteria. Serum thiols, GST, malanoldehyde (MDA) and urine thiols were determined by spectrophotometer based methods. Results: Serum thiols and urine thiols were significantly decreased (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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