Industry affiliation influence on randomized controlled trials for platelet-rich plasma in the treatment of lateral epicondylitis: a systematic review

Autor: Justin B. Castonguay, BA, Jacob L. Kotlier, BA, Amir Fathi, BS, Frank A. Petrigliano, MD, Joseph N. Liu, MD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: JSES International, Vol 8, Iss 6, Pp 1284-1289 (2024)
Druh dokumentu: article
ISSN: 2666-6383
DOI: 10.1016/j.jseint.2024.06.010
Popis: Background: Explicit funding and industry affiliation are believed to potentially impact medical research. There have been an increasing number of studies that have evaluated this relationship. The purpose of this study is to determine whether industry affiliation influences the outcomes of randomized controlled trials that investigate the effectiveness of platelet-rich plasma (PRP) in the treatment of lateral epicondylitis. Methods: A search of PubMed, SPORTDiscus, and SCOPUS was performed using the search terms “lateral epicondylitis” and “platelet-rich plasma” as well as “tennis elbow” and “platelet-rich plasma.” Only studies from 2010 to present were considered. Final texts were then analyzed for industry affiliation and treatment efficacy. When determining whether a study was industry-affiliated, explicit financial supporters of the study, stated conflicts of interest, American Academy of Orthopaedic Surgeons disclosures, and the Centers for Medicare and Medicaid Services open payments database were assessed. Study outcomes were categorized as favorable, analogous, or unfavorable based on achieving a statistically significant (P
Databáze: Directory of Open Access Journals