New modalities of allergen immunotherapy

Autor: Manish Ramesh, Merhunisa Karagic
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Human Vaccines & Immunotherapeutics, Vol 14, Iss 12, Pp 2848-2863 (2018)
Druh dokumentu: article
ISSN: 2164-5515
2164-554X
21645515
DOI: 10.1080/21645515.2018.1502126
Popis: Allergen immunotherapy is a rapidly evolving field. Although subcutaneous immunotherapy has been practiced for over a hundred years, improved understanding of the underlying immunological mechanisms has led to the development of new, efficacious and better tolerated allergen-derivatives, adjuvants and encapsulated allergens. Diverse routes of allergen immunotherapy – oral, sublingual, epicutanoeus and intralymphatic – are enabling immunotherapy for anaphylactic food allergies and pollen-food allergy syndrome, while improving the tolerability and effectiveness of aeroallergen immunotherapy. The addition of Anti-IgE therapy decreases adverse effects of subcutaneous and oral immunotherapy.
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