| Autor: |
Tero Ylisaukko-oja, Clas-Göran af Björkesten, Anja Eberl, Heikki Nuutinen, Airi Jussila, Pauliina Molander, Ritva Koskela, Timo Blomster, Markku Pajala, Tuire Ilus, Paula Haiko, Bianca Kovac, Saija Silvola, Sarah Smith, Jari Jokelainen, Taina Sipponen |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Heliyon, Vol 10, Iss 12, Pp e32432- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2405-8440 |
| DOI: |
10.1016/j.heliyon.2024.e32432 |
| Popis: |
Purpose: To analyze treatment persistence and treatment outcomes of vedolizumab as first-line biological treatment in Crohn's disease (CD) and ulcerative colitis (UC) patients in a Finnish real-world setting. Methods: Observational, retrospective, multi-center chart review study that included adult CD and UC patients initiating vedolizumab as first-line biological treatment between 2014 and 2020. Results: The cohort consisted of 54 CD and 69 UC patients. At month 12, treatment persistence was 84.9 % in CD and 64.7 % in UC. Most vedolizumab discontinuations (CD, n = 11; UC, n = 26) were due to inefficacy. Discontinuations due to adverse events were rare (n |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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