Defining functional interactions during biogenesis of epithelial junctions

Autor: J. C. Erasmus, S. Bruche, L. Pizarro, N. Maimari, T. Poggioli, C. Tomlinson, J. Lees, I. Zalivina, A. Wheeler, A. Alberts, A. Russo, V. M. M. Braga
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms13542
Popis: Formation and reinforcement of E-cadherin-mediated adhesion depends on intracellular trafficking and interactions with the actin cytoskeleton, but how these are coordinated is not known. Here the authors conduct a focused phenotypic screen to identify new pathways regulating cell–cell junction homeostasis.
Databáze: Directory of Open Access Journals