Impact of lag time on lung function impairment in pulmonary tuberculosis sequelae patients – A cross-sectional study

Autor: Sreekaanth S, Ragulan Rajalingam, Jereen Varghese, Viswambhar V, Vidhya Priya
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Asian Journal of Medical Sciences, Vol 14, Iss 8, Pp 207-210 (2023)
Druh dokumentu: article
ISSN: 2467-9100
2091-0576
DOI: 10.3126/ajms.v14i8.47789
Popis: Background: Treatment completed pulmonary tuberculosis (PTB) patients are often left with permanent pulmonary function impairment. Lag time remains a major factor in determining the severity of the sequelae. Aims and Objectives: This study aims to assess the impact of lag time on PTB sequelae. Materials and Methods: A cross-sectional study was conducted during July 2019–December 2020. A total of 85 patients presenting with clinicoradiological features of PTB sequelae were recruited for the study and spirometry and diffusion capacity of lungs (DLCO) were done. They were divided into study groups based on lag time. The lag time (in days) was considered as primary explanatory variable. One-way ANOVA and Chi-square tests were used. coGuide V.1.0 was used for statistical analysis. Results: The mean lag time was 52.94 days in the study population. The mean duration of after treatment was 15.45 years in the study population. There was a statistically significant difference across study groups (classified based on the lag time) in lung function such as FVC%, FEV1, FEVI/FVC, MEF, DLCO, and duration of after treatment (P
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