A case of Avelumab response to multiple bone and lymph node metastases of plasmacytoid variant bladder cancer

Autor: Kazuki Kokura, Jun Watanabe, Takaaki Takuma, Shoko Uketa, Yuichi Uemura, Masayuki Uegaki
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Urology Case Reports, Vol 47, Iss , Pp 102358- (2023)
Druh dokumentu: article
ISSN: 2214-4420
DOI: 10.1016/j.eucr.2023.102358
Popis: A 74-year-old man was diagnosed with bladder cancer and referred to our department. For definitive diagnosis, transurethral resection of the bladder tumor(TURBT) was performed. The pathological result showed plasmacytoid variant of urothelial carcinoma. Subsequently, robot-assisted radical cystectomy, lymph node dissection and ileal conduit was performed, but multiple bone metastases and periaortic lymph node metastases newly appeared 30 days later. Gemcitabine and cisplatin (GC) was started, and after 4 courses, the patient became Partial Response (PR), and was switched to Avelumab as maintenance therapy. After about 1 year of maintenance therapy, the patient is still in PR.
Databáze: Directory of Open Access Journals