Effects of 5α-dihydrotestosterone on the modulation of monocyte/macrophage response to Staphylococcus aureus: an in vitro study

Autor: Déborah Cruz Dos Santos, Rafaela de Souza Bittencout, Iago Dórea Arêas, Larissa Silva C. Pena, Carolline Florentino Almeida, Bruna Carolina de Brito Guimarães, Rafael Santos Dantas Miranda Dórea, Thiago Macêdo Lopes Correia, Manoel Neres Santos Júnior, Lorena Lôbo Brito Morbeck, Talita Costa Dos Santos, Clarissa Leal S. Souza, Samira Itana de Souza, Telma de Jesus Soares, Regiane Yatsuda, Guilherme Barreto Campos, Lucas Miranda Marques
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Biology of Sex Differences, Vol 14, Iss 1, Pp 1-17 (2023)
Druh dokumentu: article
ISSN: 2042-6410
DOI: 10.1186/s13293-023-00501-2
Popis: Highlights A sex difference in the immune response to S. aureus was observed. DHT stimulated a greater release of inflammatory cytokines. DHT promoted the activation of genes involved in this response. DHT suppressed the release of inflammatory markers.
Databáze: Directory of Open Access Journals
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