A Rare Case of Sino-Nasal Teratocarcinosarcoma (Response to Induction Chemotherapy)

Autor: Muhammad Haris Rauf, Asma Asghar, Ali Zafar Sheikh,, Anis-ur-Rehman,, Kashif Siddique,
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Pakistan Armed Forces Medical Journal, Vol 74, Iss 3 (2024)
Druh dokumentu: article
ISSN: 0030-9648
2411-8842
DOI: 10.51253/pafmj.v74i3.12104
Popis: We are presenting a rare case of sino-nasal teratocarcinosarcoma. A 43-year-old male patient presented with repeated episodes of epistaxis and headache for 3 months. On examination, the ENT consultant noticed a mass in the right nasal cavity for which biopsy was performed and CT scan advised. Sinonasal teratocarcinosarcoma was diagnosed on biopsy and immunohistochemistry. CT Face followed by PET/CT showed a FDG-avid soft tissue density mass in the right nasal cavity extending locally with a standardised uptake value of 7.4 with no distant metastasis. Surgical debulking is the first line of treatment as per the literature; however, in this case, the multidisciplinary tumour board initiated induction chemotherapy of 02 cycles of CISP/DOC owing to marked local extension of the tumour. Subsequent CT scan of the face shows a good treatment response with shrinkage of the sinonasal mass. After successful chemotherapy, the patient is now scheduled for radiotherapy and subsequently follow-up to assess the response.
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