Depressive disorders among patients with gastric cancer in Taiwan: a nationwide population-based study

Autor: Li-Yu Hu, Chia-Jen Liu, Chiu-Mei Yeh, Ti Lu, Yu-Wen Hu, Tzeng-Ji Chen, Pan-Ming Chen, Shyh-Chyang Lee, Cheng-Ho Chang
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: BMC Psychiatry, Vol 18, Iss 1, Pp 1-8 (2018)
Druh dokumentu: article
ISSN: 1471-244X
DOI: 10.1186/s12888-018-1859-8
Popis: Abstract Background In cancer patients, depressive disorder comorbidity is associated with greater suicide risk and poorer treatment outcomes, quality of life, and adherence to treatment. The aim of the study was to evaluate the incidence of newly-diagnosed depressive disorders after a gastric cancer diagnosis compared with a matched cohort using the National Health Insurance Research Database in Taiwan. Methods We conducted a retrospective cohort study of 57,506 patients (28,753 patients with gastric cancer and 28,753 matched patients) selected from the National Health Insurance Research Database. Patients were observed for a maximum of 12 years to determine the incidence of newly-diagnosed depressive disorders. Also, a Cox regression analysis which included death as an independent censor was performed to identify the potentially predictive variables for developing subsequent depressive disorders following a cancer diagnosis among the patients suffering from gastric cancer. Results The cumulative incidence of depressive disorders in the gastric cancer patients was significantly higher compared to those in the matched cohort (p
Databáze: Directory of Open Access Journals
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