Genome-wide Estimation of Evolutionary Distance and Phylogenetic Analysis of Homologous Genes

Autor: Meixia Zhao, Biao Zhang, Jianxin Ma, Damon Lisch
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Bio-Protocol, Vol 8, Iss 23 (2018)
Druh dokumentu: article
ISSN: 2331-8325
DOI: 10.21769/BioProtoc.3097
Popis: Homologous genes, including paralogs and orthologs, are genes that share sequence homologies within or between different species. Homologous genes originate from a common origin through speciation, genetic duplication or horizontal gene transfer. Estimation of the sequence divergence of homologous genes help us to understand divergence time, which makes it possible to understand the evolutionary patterns of speciation, gene duplication and gene transfer events. This protocol will provide a detailed bioinformatics pipeline on how to identify the homologous genes, compare their sequence divergence and phylogenetic relationships, focusing on homologous genes that show syntenic relationships using soybean (Glycine max) and common bean (Phaseolus vulgaris) as example species.
Databáze: Directory of Open Access Journals