Molecular Architecture and Biomedical Leads of Terpenes from Red Sea Marine Invertebrates

Autor: Mohamed Elamir F. Hegazy, Tarik A. Mohamed, Montaser A. Alhammady, Alaa M. Shaheen, Eman H. Reda, Abdelsamed I. Elshamy, Mina Aziz, Paul W. Paré
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Marine Drugs, Vol 13, Iss 5, Pp 3154-3181 (2015)
Druh dokumentu: article
ISSN: 1660-3397
DOI: 10.3390/md13053154
Popis: Marine invertebrates including sponges, soft coral, tunicates, mollusks and bryozoan have proved to be a prolific source of bioactive natural products. Among marine-derived metabolites, terpenoids have provided a vast array of molecular architectures. These isoprenoid-derived metabolites also exhibit highly specialized biological activities ranging from nerve regeneration to blood-sugar regulation. As a result, intense research activity has been devoted to characterizing invertebrate terpenes from both a chemical and biological standpoint. This review focuses on the chemistry and biology of terpene metabolites isolated from the Red Sea ecosystem, a unique marine biome with one of the highest levels of biodiversity and specifically rich in invertebrate species.
Databáze: Directory of Open Access Journals