| Autor: |
Emilie Verrecchia-Ramos, Olivier Morel, Valérie Beauchat, Sylvie Denet, Abdourahamane Djibo Sidikou, Merwan Ginet, Estelle Pfletschinger, Luminita Teodor, Maud Trombowsky, Jeany Verdier, Christelle Vère, Paul Retif, Sinan Ben Mahmoud |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
EJNMMI Physics, Vol 10, Iss 1, Pp 1-12 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2197-7364 |
| DOI: |
10.1186/s40658-023-00545-8 |
| Popis: |
Abstract Background Patient radioprotection in myocardial perfusion imaging (MPI)-SPECT is important but difficult to optimize. The aim of this study was to adjust injected activity according to patient size—weight or BMI—by using a cardiofocal collimator camera. Methods The correlation equation between size and observed counts in image was determined in patients who underwent stress Tc-99m-sestamibi MPI-SPECT/CT with a cardiofocal collimator-equipped conventional Anger SPECT/CT system. Image quality analyses by seven nuclear physicians were conducted to determine the minimum patient size-independent observed count threshold that yielded sufficient image quality for perfusion-defect diagnosis. These data generated an equation that can be used to calculate personalized activity for patients according to their size. Results Analysis of consecutive patients (n = 294) showed that weight correlated with observed counts better than body mass index. The correlation equation was used to generate the equation that expressed the relationship between observed counts, patient weight, and injected activity. Image quality analysis with 50 images yielded an observed count threshold of 22,000 counts. Using this threshold means that the injected activity in patients with |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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