Stabilin Receptors: Role as Phosphatidylserine Receptors

Autor:	Seung-Yoon Park, In-San Kim
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	stabilin-1 stabilin-2 efferocytosis phosphatidylserine fusion Microbiology QR1-502
Zdroj:	Biomolecules, Vol 9, Iss 8, p 387 (2019)
Druh dokumentu:	article
ISSN:	2218-273X
DOI:	10.3390/biom9080387
Popis:	Phosphatidylserine is a membrane phospholipid that is localized to the inner leaflet of the plasma membrane. Phosphatidylserine externalization to the outer leaflet of the plasma membrane is an important signal for various physiological processes, including apoptosis, platelet activation, cell fusion, lymphocyte activation, and regenerative axonal fusion. Stabilin-1 and stabilin-2 are membrane receptors that recognize phosphatidylserine on the cell surface. Here, we discuss the functions of Stabilin-1 and stabilin-2 as phosphatidylserine receptors in apoptotic cell clearance (efferocytosis) and cell fusion, and their ligand-recognition and signaling pathways.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/514840d76e54496e9de539df0dc2a93f Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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