Advances in the Asymmetric Synthesis of BINOL Derivatives

Autor: Everton Machado da Silva, Hérika Danielle Almeida Vidal, Marcelo Augusto Pereira Januário, Arlene Gonçalves Corrêa
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Molecules, Vol 28, Iss 1, p 12 (2022)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules28010012
Popis: BINOL derivatives have shown relevant biological activities and are important chiral ligands and catalysts. Due to these properties, their asymmetric synthesis has attracted the interest of the scientific community. In this work, we present an overview of the most efficient methods to obtain chiral BINOLs, highlighting the use of metal complexes and organocatalysts as well as kinetic resolution. Further derivatizations of BINOLs are also discussed.
Databáze: Directory of Open Access Journals
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