Differential susceptibility of mono- and di-O-alkyl ether phosphoglycerides to acetolysis.

Autor: R Kumar, S T Weintraub, D J Hanahan
Jazyk: angličtina
Rok vydání: 1983
Předmět:
Zdroj: Journal of Lipid Research, Vol 24, Iss 7, Pp 930-937 (1983)
Druh dokumentu: article
ISSN: 0022-2275
DOI: 10.1016/S0022-2275(20)37939-6
Popis: The effectiveness of acetolysis as a tool in structural characterization of mono- and di-O-alkyl phosphoglycerides was investigated. Surprisingly, it was found that the di-O-alkyl phosphoglycerides were resistant to attack during acetolysis, whereas the mono-ether types, with a free hydroxyl function or an ester on carbon-2, were easily attacked at the glycerol-phosphate bond. On the other hand, Vitride reduction occurred readily with the mono-ether or di-ether phosphoglycerides. The implications of these findings as they relate to identification of ether phospholipids in tissues are discussed.
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