| Autor: |
Luisa Vigevani, André Gohr, Thomas Webb, Manuel Irimia, Juan Valcárcel |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-017-02007-z |
| Popis: |
Several families of natural compounds target core components of the pre-mRNA splicing machinery and display anti-tumor activity. Here the authors show that particular sequence features can be linked to drug response, and that drugs with very similar chemical structures display substantially different effects on splicing regulation. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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