| Autor: |
Beatrice von Jeinsen, Stergios Tzikas, Gerhard Pioro, Lars Palapies, Tanja Zeller, Christoph Bickel, Karl J Lackner, Stephan Baldus, Stefan Blankenberg, Thomas Muenzel, Andreas M Zeiher, Till Keller |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 11, Iss 5, p e0154724 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0154724 |
| Popis: |
BACKGROUND:Common ECG criteria such as ST-segment changes are of limited value in patients with suspected acute myocardial infarction (AMI) and bundle branch block or wide QRS complex. A large proportion of these patients do not suffer from an AMI, whereas those with ST-elevation myocardial infarction (STEMI) equivalent AMI benefit from an aggressive treatment. Aim of the present study was to evaluate the diagnostic information of cardiac troponin I (cTnI) in hemodynamically stable patients with wide QRS complex and suspected AMI. METHODS:In 417 out of 1818 patients presenting consecutively between 01/2007 and 12/2008 in a prospective multicenter observational study with suspected AMI a prolonged QRS duration was observed. Of these, n = 117 showed significant obstructive coronary artery disease (CAD) used as diagnostic outcome variable. cTnI was determined at admission. RESULTS:Patients with significant CAD had higher cTnI levels compared to individuals without (median 250ng/L vs. 11ng/L; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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