Severe Sinus Bradycardia in Puumala virus infection

Autor: Andréa Pastissier, Sébastien Humbert, Pauline Naudion, Nadine Meaux-Ruault, Marc Badoz, Nadine Magy-Bertrand
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 79, Iss , Pp 75-76 (2019)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2018.11.019
Popis: Puumala orthohantavirus (PUUV) is the most prevalent of the four species of zoonotic hantaviruses found in Europe, causing nephropathia epidemica, a mild form of hemorrhagic fever with acute kidney injury that presents with elevated serum creatinine level, proteinuria and hematuria. The febrile phase of the infection begins with flu-like syndrome and visual disturbance. Laboratory results can show thrombocytopenia. The oliguric phase with elevated serum creatinine level then occurs. Cardiac involvement is sometimes observed, especially ECG abnormality: transient T-waves inversion, generally in the lateral or inferior leads. Marked bradycardia has been exceptionally described. We report the case of a 36-year-old woman with acute PUUV infection. Two days after admission, the patient presented a sinus bradycardia at 25/min. The bradycardia was asymptomatic, persisted one week and resolved spontaneously. Cardiac involvement in Puumala virus infection seems not to be associated with a bad prognosis. Bradycardia in the course of an influenza-like illness in endemic areas should suggest several pathogens such as legionella, Q fever or PUUV virus infection. Keywords: Hantaviruses, Bradycardia, Hemorrhagic fever with renal syndrome, Puumala virus, France
Databáze: Directory of Open Access Journals