A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation

Autor: Franco Lai, Lorenzo Pelagatti, Chiara Pagnini, Alessio Baldini, Daniele Versari, Simone Magazzini
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Emergency Care Journal, Vol 16, Iss 1 (2020)
Druh dokumentu: article
ISSN: 1826-9826
2282-2054
DOI: 10.4081/ecj.2020.8596
Popis: A patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on myocardial contractility. The authors present a case of a 19-year-old male of oriental-Asiatic origin admitted unconscious to ED with alcoholic fetor: on electrocardiogram a significant and widespread STsegment elevation was observed. A bedside echocardiography showed no abnormalities in segmental kinetics; therefore electrocardiogram- alterations could be related to a coronary spasm. The literature is poor about this effect induced by acute alcohol ingestion: the pathophysiological mechanism at the base of the abnormal muscle contractility, seems to be related to an impairment in cyclic guanosine monophosphate production, although a second and less probable hypothesis could be an altered intracellular concentration of calcium levels.
Databáze: Directory of Open Access Journals