Therapeutic antibodies under development for SARS‐CoV‐2

Autor: Zetong Ma, MengMei Zhu, Shuyi Zhang, Kewen Qian, Chuqi Wang, Wenyan Fu, Changhai Lei, Shi Hu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: View, Vol 3, Iss 2, Pp n/a-n/a (2022)
Druh dokumentu: article
ISSN: 2688-268X
2688-3988
DOI: 10.1002/VIW.20200178
Popis: Abstract The world is experiencing one of the most difficult moments in history with COVID‐19, which has rapidly developed into a worldwide pandemic with a significant health and economic burden. Efforts to fight the virus, including prevention and treatment, have never stopped. However, no specific drugs or treatments have yet been found. Antibody drugs have never been absent in epidemics such as SARS, MERS, HIV, Ebola, and so on in the past two decades. At present, while research on the SARS‐CoV‐2 vaccine is in full swing, antibody drugs are also receiving widespread attention. Several antibody drugs have successfully entered clinical trials and achieved impressive therapeutic effects. Here, we summarize the therapeutic antibodies against SARS‐CoV‐2, as well as the research using ACE2 recombinant protein or ACE2‐Ig fusion protein.
Databáze: Directory of Open Access Journals