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Bashair M Mussa,1 Mia Schauman,2 Vijay Kumar,3 Sijomol Skaria,3 Salah Abusnana4,51Basic Medical Science Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; 2Medical Research Department, Celolab, Dubai, United Arab Emirates; 3Rashid Centre for Diabetes and Research, Ajman, United Arab Emirates; 4Clinical Science Department, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; 5Diabetes and Endocrinology Department, University Hospital Sharjah, Sharjah, United Arab EmiratesBackground: There is growing evidence that stress and sleep deprivation are involved in development of type 2 diabetes (T2DM). The latter is one of the most challenging health problems in the UAE. Therefore, the present study aimed to investigate the effects of personalized intervention on glycemic and weight control in Emirati patients with T2DM. The intervention involved assessment and modification of stress levels and sleep patterns.Methods: This was a randomized controlled study conducted on 51 Emirati patients with T2DM (age 18–60 years, body-mass index (BMI) ≥25 kg/m2): those in the intervention group who completed the trial numbered 18 and those in the control group who completed the trial numbered 17. Heart-rate variability was used for real-life and long-term assessments of stress, sleep, and recovery. Body weight, BMI, HbA1c and lipid profile were included in the investigation. The National Clinical Trial identifier number is NCT03644134.Results: Percentage change in body weight was significantly greater (P |