Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment

Autor: Carlota Rubio-Perez, Ester Planas-Rigol, Juan L. Trincado, Ester Bonfill-Teixidor, Alexandra Arias, Domenica Marchese, Catia Moutinho, Garazi Serna, Leire Pedrosa, Raffaella Iurlaro, Francisco Martínez-Ricarte, Laura Escudero, Esteban Cordero, Marta Cicuendez, Sara Ruiz, Genís Parra, Paolo Nuciforo, Josep Gonzalez, Estela Pineda, Juan Sahuquillo, Josep Tabernero, Holger Heyn, Joan Seoane
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-21789-x
Popis: The use of CSF for diagnosis of metastatic brain tumors could be of clinical and patient benefit. Here the authors undertake a single-cell RNA analysis of CSF and brain to determine whether the phenotype in the CSF is reflective of the phenotype in the tumor.
Databáze: Directory of Open Access Journals