Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes

Autor: Xuemei Ge, Shang Wu, Wen Shen, Lijuan Chen, Yan Zheng, Fen Ao, Yuanlan Ning, Yueyang Mao, Zhong Chen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Bioengineering, Vol 9, Iss 4, p 130 (2022)
Druh dokumentu: article
ISSN: 2306-5354
DOI: 10.3390/bioengineering9040130
Popis: In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF–AuNPs nanofiber membrane could potentially be applied for nerve regeneration.
Databáze: Directory of Open Access Journals
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