Autor: |
Xuemei Ge, Shang Wu, Wen Shen, Lijuan Chen, Yan Zheng, Fen Ao, Yuanlan Ning, Yueyang Mao, Zhong Chen |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Bioengineering, Vol 9, Iss 4, p 130 (2022) |
Druh dokumentu: |
article |
ISSN: |
2306-5354 |
DOI: |
10.3390/bioengineering9040130 |
Popis: |
In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF–AuNPs nanofiber membrane could potentially be applied for nerve regeneration. |
Databáze: |
Directory of Open Access Journals |
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