Autor: |
Yening Zhang, Yi He, Ying Pang, Zhongge Su, Yu Wang, Yuhe Zhou, Yongkui Lu, Yu Jiang, Xinkun Han, Lihua Song, Liping Wang, Zimeng Li, Xiaojun Lv, Yan Wang, Juntao Yao, Xiaohong Liu, Xiaoyi Zhou, Shuangzhi He, Lili Song, Jinjiang Li, Bingmei Wang, Lili Tang |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMC Psychology, Vol 12, Iss 1, Pp 1-11 (2024) |
Druh dokumentu: |
article |
ISSN: |
2050-7283 |
DOI: |
10.1186/s40359-024-01607-x |
Popis: |
Abstract Purpose The pathways underpinning suicide ideation (SI) and certain physical and psychological factors in patients with advanced breast cancer remain unclear. This study develops and validates a mediation model that delineates the associations between several multidimensional variables and SI in Chinese patients with advanced breast cancer. Methods Patients with advanced breast cancer (n = 509) were recruited as study participants from 10 regional cancer centers across China from August 2019 to December 2020. Participants were required to complete five questionnaires using an electronic patient-reported outcomes (ePRO) system: 9 item- Patient Health Questionnaire (PHQ-9), Hospital Anxiety and Depression Scale (HADS), Insomnia Severity Index (ISI), 5-level EQ-5D (EQ-5D-5L), and MD Anderson Symptom Inventory (MDASI). Risk factors for SI were identified using multivariable logistic regression, and inputted into serial multiple mediation models to elucidate the pathways linking the risk factors to SI. Results SI prevalence was 22.8% (116/509). After adjusting for covariates, depression (odds ratio [OR] = 1.384), emotional distress (OR = 1.107), upset (OR = 0.842), and forgetfulness (OR = 1.236) were identified as significant independent risk factors (all p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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