Prediction of serum neuritin and neuron-specific enolase for prognosis in patients with traumatic brain injury combined with spinal cord injury
| Autor: | Pu Bingbing, Chen Yu, Bi Qingguo, Shen Jian, Wang Lihui, Han Ye |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Medical Biochemistry, Vol 43, Iss 6, Pp 870-878 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1452-8258 1452-8266 |
| DOI: | 10.5937/jomb0-45469 |
| Popis: | Background: Serum neuritin and neuron-specific enolase (NSE) have predictive value for the prognosis of patients with combined traumatic brain injury (TBI) and spinal cord injury (SCI). Studying their predictive effects has positive value for disease control and treatment. Methods: Sixty patients with combined TBI and SCI were recruited and rolled into three groups according to prognosis: Group I (n=42, favourable prognosis), Group II (n=11, poor prognosis), and Group III (n=7, death). Clinical indicators were compared between the groups, and the predictive value of different indicators for prognosis was analyzed. Results: The proportion of patients with combined injuries to other organs and hypotension, as well as levels of platelets (PLT), D-dimer (D-D), antithrombin III (AT-III), S100 protein (S100 ), NSE, and serum neurofilament levels were significantly higher in Groups II and III compared to Group I. Conversely, the Glasgow Coma Scale (GCS) scores were significantly lower in Group I (P |
| Databáze: | Directory of Open Access Journals |
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