Depression and incident cardiovascular disease among patients with chronic kidney disease

Autor: Anthony D'Oro, Devansh Himanshu Patel, Sojin Wass, Trygve Dolber, Khurram Nasir, Mirela Dobre, Mahboob Rahman, Sadeer Al-Kindi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 18, Iss , Pp 200199- (2023)
Druh dokumentu: article
ISSN: 2772-4875
DOI: 10.1016/j.ijcrp.2023.200199
Popis: Background: Depression is associated with an increased risk of cardiovascular disease (CVD) and is prevalent among patients with chronic kidney disease (CKD). We aimed to identify the association of depression with incident CVD. Methods: We studied patients with CKD stages 2–4 enrolled in the Chronic Renal Insufficiency Cohort (CRIC) and excluded participants with preexisting CVD. The Cox proportional hazard model was used to examine the association between baseline depression [Beck's Depression Inventory (BDI) score ≥11] and incidence of CVD (cerebrovascular accident, myocardial infarction, heart failure, or peripheral artery disease). Models were adjusted for age, sex, race, estimated glomerular filtration rate (eGFR), urine albumin-creatinine ratio (UACR), systolic and diastolic blood pressure, and 10-year estimated CVD risk. Results: Among 2585 CRIC study participants, 640 (25%) patients had depression at study baseline. Compared to patients without depression, patients with depression were more likely to be women (56% vs. 46%), non-White (68% vs. 53%), with household income
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