A Comparison of Immunohistochemical Expression of Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 in Dental Follicles with Different Radiographic Sizes

Autor: Shirin Saravani, amed Nemati Rezvani, Mehrdad Shahraki, Hamideh Kadeh
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Iranian Journal of Medical Sciences, Vol 49, Iss 8, Pp 508-514 (2024)
Druh dokumentu: article
ISSN: 0253-0716
1735-3688
32526415
DOI: 10.30476/ijms.2023.98602.3121
Popis: Background: Odontogenic cysts and tumors develop from the dental follicle of asymptomatic impacted teeth. Odontogenic tissues express the epidermal growth factor receptor family (EGFR), which mediates cell proliferation, survival, and neoplastic differentiation. The present study aimed to compare the immunohistochemical expression of EGFR and human epidermal growth factor receptor 2 (HER2) in the dental follicle of impacted wisdom teeth with normal and abnormal radiographic size.Methods: In this analytical study, immunohistochemical staining of EGFR and HER2 was performed on 30 normal and 30 abnormal follicles of impacted third molars. Follicles with a width of
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