Quantify the Effect of Air Gap Errors on Skin Dose for Breast Cancer Radiotherapy

Autor: Chunbo Tang MS, Jun Yuan, Hailiang Guo BS, Zhongyang Dai, Biaoshui Liu MS, Haiyan Xi MS, Ji He PhD, Shanzhou Niu PhD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Technology in Cancer Research & Treatment, Vol 23 (2024)
Druh dokumentu: article
ISSN: 1533-0338
15330338
DOI: 10.1177/15330338241258566
Popis: Purpose: Determining the impact of air gap errors on the skin dose in postoperative breast cancer radiotherapy under dynamic intensity-modulated radiation therapy (IMRT) techniques. Methods: This was a retrospective study that involved 55 patients who underwent postoperative radiotherapy following modified radical mastectomy. All plans employed tangential IMRT, with a prescription dose of 50 Gy, and bolus added solely to the chest wall. Simulated air gap depth errors of 2 mm, 3 mm, and 5 mm were introduced at depression or inframammary fold areas on the skin, resulting in the creation of air gaps named Air2, Air3, and Air5. Utilizing a multivariable GEE, the average dose ( D mean ) of the local skin was determined to evaluate its relationship with air gap volume and the lateral beam's average angle (AALB). Additionally, an analysis was conducted on the impact of gaps on local skin. Results: When simulating an air gap depth error of 2 mm, the average D mean in plan2 increased by 0.46 Gy compared to the initial plan (planO) ( p
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