| Autor: |
Christopher Darwen, Angella Bryan, Tanviha Quraishi-Akhtar, John Moore |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
BJA Open, Vol 5, Iss , Pp 100124- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2772-6096 |
| DOI: |
10.1016/j.bjao.2023.100124 |
| Popis: |
Background: Blood lactate concentration in the postoperative period is a marker of physiological stress and a predictor of complications and mortality. Cardiopulmonary exercise testing (CPET) is a common preoperative risk stratification tool. We aimed to investigate the association between preoperative CPET results and postoperative lactate concentration with postoperative mortality after major noncardiac surgery. Methods: We analysed data from patients undergoing major noncardiac surgery in a tertiary UK centre between 2007 and 2014 who had preoperative CPET and postoperative lactate measurements. Univariate and multivariate analyses were performed to assess the association between lactate concentration, CPET results, or both and mortality. Results: We analysed data from 1075 patients. A mean lactate concentration >2 mM in the first 12, 24, and 48 h after surgery was associated with odds ratios (ORs) and 95% confidence intervals (CIs) for 30-day mortality of 3.9 (2.1–7.3; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
