| Autor: |
Jovica Jovanović, Marjan Muratović, Dejan Petković, Dejan Krstić, Dušan Sokolović, Boris Đinđić |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Acta Medica Medianae, Vol 49, Iss 1, Pp 37-42 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
0365-4478 |
| Popis: |
Microwave radiation MWR is widespread in human environment. The most frequent sources of MWR are mobile phones and cell towers. The effects of MWR are still unknown and there are insufficient data about long-term MWR effects on hepatocytes and brain structures.The aim of this paper was to investigate the biological effects of mobile phone microwave radiation on the brain and liver of experimental animals and to determine the increase in oxidative stress as a possible pathogenetic mechanism for harmful effects of long-term exposure.Wistar rats, 3 months old, were divided into two groups: I-rats constantly exposed to MWR (3 female and 2 male) and II-control animals without near source of electromagnetic field (EMF) (3 female and 2 male). The microwave radiation was produced by a mobile test phone (model NOKIA 3110; Nokia Mobile Phones Ltd.) connected to a Communication Test Set (model 4202S; Wavetek, Germany). A 900 MHz electromagnetic near-field signal for GSM (Global System for Mobile communication at 900 MHz, continuous wave, analog phone) system was used. The whole-body specific energy absorption (SAR) rate was estimated as 0.025-0.05 W/kg (E=9.8-18.3 V/m, B=4.8-8.6 µT). Rats were sacrificed after 3 months of MWR exposure. The liver and brain were fixed in 10% formaldehyde and paraffin sections were stained by HE. The biochemical analyses comprised the determination of serum activity of AST (Aspartate aminotransferase), ALT (Alanine transaminase), GGT (Gamma-glutamyl transpeptidase) and LDH (Lactate dehydrogenase), as well as determination of serum concentration of sodium, potassium and chloride. Lipid peroxidation was determined by measuring the quantity of malondialdehyde (MDA).Slightly increased number of micronuclei and discrete perivenular fatty changes were only histopathological findings in the liver of exposed rats. The discrete reduction of gray matter and reduced size and number of dendritic spines of Purkinje cells in cerebellum were notified as well. The serum activity of ALT was significantly increased (p |
| Databáze: |
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