Microneurografia e pletismografia de oclusão venosa na insuficiência cardíaca: correlação com prognóstico Microneurografía y pletismografía de oclusión venosa en la insuficiencia cardiaca: correlación con pronóstico Microneurography and venous occlusion plethysmography in heart failure: correlation with prognosis

Autor: Robinson Tadeu Munhoz, Carlos Eduardo Negrão, Antonio Carlos Pereira Barretto, Marcelo Eidi Ochiai, Juliano Novaes Cardoso, Paulo Cesar Morgado, Carlos Henrique Del Carlo, José Antonio Franchini Ramires
Jazyk: English<br />Portuguese
Rok vydání: 2009
Předmět:
Zdroj: Arquivos Brasileiros de Cardiologia, Vol 92, Iss 1, Pp 46-53 (2009)
Druh dokumentu: article
ISSN: 0066-782X
1678-4170
DOI: 10.1590/S0066-782X2009000100008
Popis: FUNDAMENTO: Microneurografia e pletismografia de oclusão venosa podem ser considerados métodos de avaliação da atividade simpática. OBJETIVO: Avaliar a intensidade da atividade simpática através da microneurografia e da pletismografia de oclusão venosa em pacientes com insuficiência cardíaca, e correlacionar essa intensidade com prognóstico. MÉTODOS: 52 pacientes com insuficiência cardíaca (FE 53,5 impulsos/min para ANSM (S=90,55. E=73,68%) e 1,81 ml/min/100gr (PFUNDAMENTO: Microneurografía y pletismografía de oclusión venosa se pueden considerar como métodos de evaluación de la actividad simpática. OBJETIVO: Evaluar la intensidad de la actividad simpática a través de la microneurografía y de la pletismografía de oclusión venosa en pacientes con insuficiencia cardiaca, y correlacionar esa intensidad con pronóstico. MÉTODOS: Un total de 52 pacientes con insuficiencia cardiaca (FE 53,5 impulsos/min para ANSM (S=90,55. E=73,68%) y 1,81 ml/min/100gr (PBACKGROUND: Microneurography and venous occlusion plethysmography can be considered methods of assessment of the sympathetic activity. OBJECTIVE: To evaluate the intensity of the sympathetic activity through microneurography and venous occlusion plethysmography in patients with heart failure (HF) and correlate this intensity with prognosis. METHODS: 52 patients with HF (ejection fraction < 45% at the echocardiogram): 12 with FCII and 40 with FCIV. After compensation, the muscular sympathetic nervous activity (MSNA) in the peroneal nerve (microneurography) and the muscular blood flow (MBF) in the forearm were evaluated (venous occlusion plethysmography). After an 18-month follow-up, the patients were divided in 3 groups: 12 with FCII, 19 with FCIV that did not die and 21 with FCIV that died. The intensity of the sympathetic activity was compared in the three different groups. RESULTS: Patients with FCII presented lower MSNA (p=0.026) and higher MBF (p=0.045) than the ones with FCIV that did not die. The patients with FCIV that died presented higher MSNA (p53.5 impulses/min for MSNA (S=90.55. E=73.68%) and < 1.81 ml/min/100gr for MBF (S=90.4%. E=73.7%). Kaplan-Meier curve: higher survival with MSNA < 53.5 impulses/min (p1.81 ml/min/100gr (P
Databáze: Directory of Open Access Journals
Externí odkaz: