The effect of silk peptide on immune system, A randomized, double-blind, placebo-controlled clinical trial

Autor: Jin-Taek Hwang, Jung Min Cho, In Hye Jeong, Jeong-yong Lee, Ki-Chan Ha, Hyang-Im Baek, Hye Jeong Yang, Min Jung Kim, Jong Ho Lee
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Functional Foods, Vol 55, Iss , Pp 275-284 (2019)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2019.02.032
Popis: In this study, we evaluated the immunostimulatory effect of silk peptide in subjects with peripheral blood leukocyte levels of 4–8 × 103/μl by a randomized, double-blind, placebo-controlled clinical trial. The subjects were randomly assigned to one of two groups, the placebo control or silk peptide intervention group, for 8 weeks. As a result, evaluation of efficacy in 97 subjects showed no significant difference between the groups in immunostimulatory parameters. However, after separate analysis of 61 non-season influenza vaccine subjects, the natural killer cell activity (%) with an effector cell: target cell (E: T) ratio of 10:1 was increased significantly from 30.7 ± 2.28% at week 0 to 41.8 ± 2.71% at week 8 (p
Databáze: Directory of Open Access Journals