Development and diversity of lactic acid producing bacteria and bifidobacteria in healthy full term Indian infants from Himachal Pradesh

Autor: Sampan Attri, Rishi Mahajan, Gunjan Goel
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Intestinal Research, Vol 16, Iss 4, Pp 529-536 (2018)
Druh dokumentu: article
ISSN: 1598-9100
2288-1956
DOI: 10.5217/ir.2018.00050
Popis: Background/Aims The initial microbial colonization is a crucial step for the healthy development of an infant. Previous studies from India reported the dominance of target microbial species among Indian infants without any analysis on the diversity of target groups. This is the first study from India with an objective to investigate the establishment and diversity of lactic acid producing bacteria (LAB) and bifidobacteria in vaginally delivered, full term, breastfed infants for the first 4 months after birth. Methods Present study used polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) based sequence analysis of LAB and bifidobacteria in healthy infants. The results were used to compare the development and early colonization by LAB and bifidobacteria using diversity indices during the initial months of development of gut microbiota in infants. Results During the first 4 months, the Shannon diversity index (H) of LAB increased from 1.16 to 1.318 and for bifidobacteria the H increased from 0.975 to 1.293 (P
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