Global trends in gut microbiota and clostridioides difficile infection research: A visualized study

Autor: Zitong Li, Haoran Ke, Qianyun Lin, Zefeng Shen, Ye Chen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Infection and Public Health, Vol 15, Iss 7, Pp 806-815 (2022)
Druh dokumentu: article
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2022.06.011
Popis: Background: Clostridioides (clostridium) difficile infection (CDI) is the most common cause of nosocomial diarrheal disease, which has become a public health problem worldwide; gut dysbiosis plays a central role in its pathophysiology. This study conducted a bibliometric analysis of publications on gut microbiota and CDI to summarize the current status of research including research hotspots. Methods: Relevant publications from January 2004 to February 2022 were identified from the Web of Science Core Collection. Three bibliometric tools were used to perform visualization analyses. Results: A total of 1983 publications were analyzed. Annual publications increased from 11 in 2004–237 in 2021, with the US being the leading producer (47.55 % of all papers). EG Pamer had the highest average citations per article (average citations per item = 153.03, H-index = 29). Frontiers in Microbiology published the most papers. The main research foci were “fecal microbiota transplantation,” “colonization resistance,” and “multidrug-resistant bacteria.” The keywords with the highest frequency in recent years include: gut dysbiosis, antibiotic resistance, bile-acids, 16 s sequencing, multidrug-resistant bacteria, and short chain fatty acids. Conclusions: Gut microbiota and CDI is likely to remain a prominent area of research in the foreseeable future. Current research hotspots (“fecal microbiota transplantation,” “colonization resistance,” and “multidrug-resistant bacteria”) should receive even more attention in future studies.
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