| Autor: |
Maria Angelica Cortez, Fatemeh Masrorpour, Cristina Ivan, Jie Zhang, Ahmed I. Younes, Yue Lu, Marcos R Estecio, Hampartsoum B. Barsoumian, Hari Menon, Mauricio da Silva Caetano, Rishab Ramapriyan, Jonathan E. Schoenhals, Xiaohong Wang, Ferdinandos Skoulidis, Mark D. Wasley, George Calin, Patrick Hwu, James W. Welsh |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-020-18617-z |
| Popis: |
The mechanisms underlying resistance to immunotherapy are still poorly understood. Here, the authors show that BMP7, a molecule part of the TGF-beta superfamily, suppresses proinflammatory antitumor responses and may represent a target for overcoming resistance to PD1 inhibitors. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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