Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol
| Autor: | A. Baldi, K. Sejrsen, S. Purup, L. Sangalli, R. Rebucci, E. Fusi |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Italian Journal of Animal Science, Vol 4, Iss 2s, Pp 485-487 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1594-4077 1828-051X |
| DOI: | 10.4081/ijas.2005.2s.485 |
| Popis: | Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium species and it is a contaminant of food and feeds (O’Brien et al., 2001). OTA is a nephrotoxic, carcinogenic and teratogenic compound and one of the most sensible species among domestic animals is the pig (JECFA, 2001). Production of free radicals or reactive oxygen species (ROS) leading to lipid peroxidation was suggested to be one of the mechanisms by which OTA damages the cell (Rahimtula et al., 1988). |
| Databáze: | Directory of Open Access Journals |
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