Performance of diffusion and perfusion MRI in evaluating primary central nervous system lymphomas of different locations

Autor: Zhen Xing, Nannan Kang, Yu Lin, Xiaofang Zhou, Zebin Xiao, Dairong Cao
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Medical Imaging, Vol 20, Iss 1, Pp 1-6 (2020)
Druh dokumentu: article
ISSN: 1471-2342
DOI: 10.1186/s12880-020-00462-7
Popis: Abstract Background Diffusion and perfusion MRI can invasively define physical properties and angiogenic features of tumors, and guide the individual treatment. The purpose of this study was to investigate whether the diffusion and perfusion MRI parameters of primary central nervous system lymphomas (PCNSLs) are related to the tumor locations. Methods We retrospectively reviewed the diffusion, perfusion, and conventional MRI of 68 patients with PCNSLs at different locations (group 1: cortical gray matter, group 2: white matter, group 3: deep gray matter). Relative maximum cerebral blood volume (rCBVmax) from perfusion MRI, minimum apparent diffusion coefficients (ADCmin) from DWI of each group were calculated and compared by one-way ANOVA test. In addition, we compared the mean apparent diffusion coefficients (ADCmean) in three different regions of control group. Results The rCBVmax of PCNSLs yielded the lowest value in the white matter group, and the highest value in the cortical gray matter group (P
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