Genes of APOA5 and APOH apoliproteins as regulators of lipoprotein metabolism

Autor:	N. S. Shirokova, S. V. Mikhailova, D. E. Ivanoshchuk, E. V. Shachtshneider
Jazyk:	ruština
Rok vydání:	2020
Předmět:	apolipoproteins atherosclerosis triglycerides apoa5 gene apoh gene Diseases of the blood and blood-forming organs RC633-647.5 Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Атеросклероз, Vol 16, Iss 3, Pp 53-60 (2020)
Druh dokumentu:	article
ISSN:	20200307 2078-256X
DOI:	10.15372/ATER20200307
Popis:	Atherosclerosis is main cause of cardiovascular disease leading to disability and death worldwide. Many factors can affect atherogenesis, including hypertension, smoking, diabetes mellitus and inflammatory processes. It is known that disorders of cholesterol and triglycerides It is known, that violation in cholesterol and triglyceride metabolism caused by substitutions in the structure of apolipoproteins are associated with a predisposition to hyperlipidemia and atherosclerosis. Despite the increased interest in the atherogenesis mechanisms, many participants in this process are not fully understood. In this review, we examined the structure and functions of two proteins – apolipoprotein A5 and apolipoprotein H in connection with their association with impaired lipid metabolism.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/500b0db8633149a19c8f6cab0d6dc095 Zobrazit plný text záznamu View record in DOAJ