| Autor: |
Caterina Maffeis, Daniel Armando Morris, Evgeny Belyavskiy, Martin Kropf, Aravind Kumar Radhakrishnan, Veronika Zach, Cristina Rozados da Conceicao, Tobias Daniel Trippel, Elisabeth Pieske‐Kraigher, Andrea Rossi, Burkert Pieske, Frank Edelmann |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
ESC Heart Failure, Vol 8, Iss 1, Pp 116-128 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2055-5822 |
| DOI: |
10.1002/ehf2.13143 |
| Popis: |
Abstract Aims Exercise intolerance is the leading manifestation of heart failure with preserved or mid‐range ejection fraction (HFpEF or HFmrEF), and left atrial (LA) function might contribute to modulating left ventricular filling and pulmonary venous pressures. We aim to assess the association between LA function and maximal exercise capacity in patients with HFpEF or HFmrEF. Methods and results Sixty‐five patients, prospectively enrolled in the German HFpEF Registry, were analysed. Inclusion criteria were New York Heart Association functional class ≥ II, left ventricular ejection fraction > 40%, structural heart disease or diastolic dysfunction, and elevated levels of N terminal pro brain natriuretic peptide (NT‐proBNP). LA function was evaluated through speckle‐tracking echocardiography by central reading in the Charité Academic Echocardiography core lab. All patients underwent maximal cardiopulmonary exercise test and were classified according to a peak VO2 cut‐off of prognostic value (14 mL/kg/min). NT‐pro‐BNP was measured. Twenty‐nine patients (45%) reached a peak VO2 |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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