Severe reaction in a child with asymptomatic codfish allergy: Food challenge reactivating recurrent pancreatitis

Autor: Pellegrino Katia, D’Urbano Leila, Artesani Maria, Riccardi Carla, Mancini Sandro, Bella Sergio, Alghisi Federico, Cavagni Giovanni
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Italian Journal of Pediatrics, Vol 38, Iss 1, p 16 (2012)
Druh dokumentu: article
ISSN: 1824-7288
1720-8424
DOI: 10.1186/1824-7288-38-16
Popis: Abstract An 8-year-old child during the first year of life manifested severe atopic dermatitis and chronic diarrhea with mucorrhea and rectal bleeding; a fish-free diet was started based on weakly positive skin-prick tests to codfish extract. At the age of 4 years the child began to suffer of recurrent pancreatitis. When he came to our attention for the evaluation of his fish allergy, he was asymptomatic; a weak reactivity to codfish was observed (SPTs: cod, 4 mm, sIgE ImmunoCAP: cod, 1.30kU/l). The food challenge test with cod was negative. When the child ate cod again, within 5 minutes, developed anaphylactic reaction and complained of abdominal pain compatible with pancreatitis (enzyme serum levels risen and parenchymal oedema at ultrasonography), that resolved within 7 days after specific therapy. This case raises two issues: the elimination diet in asymptomatic food allergy on the basis only of SPT and the ethicality of food challenge in gastrointestinal chronic disease.
Databáze: Directory of Open Access Journals
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