Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary

Autor: A. M. Hinson, C. W. Smith, E. R. Siegel, B. C. Stack
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: International Journal of Dentistry, Vol 2014 (2014)
Druh dokumentu: article
ISSN: 1687-8728
1687-8736
DOI: 10.1155/2014/452737
Popis: The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and microbiology (including demographics, immunocompromised associations, clinical signs and symptoms, disease severity, antibiotic and surgical treatments, and recovery status) validating that infection should still be considered a prime component in the multifactorial disease.
Databáze: Directory of Open Access Journals