Pulmonary Embolism in COVID-19 Treated with VA-ECLS and Catheter tPA

Autor: Arda Akoluk, Usman Mazahir, Steven Douedi, Adel Aziz, Aref Obagi, Daniel Kiss, Daniel Flynn, Eric Costanzo, Sinan A Simsir, Matthew D Saybolt
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, Vol 14 (2020)
Druh dokumentu: article
ISSN: 1179-5484
11795484
DOI: 10.1177/1179548420957451
Popis: Background: Novel coronavirus 2019 (COVID-19) has been the focus of the medical world since being declared a pandemic in March 2020. While the pathogenesis and heterogeneity of COVID-19 manifestations is still not fully understood, viral evasion of cellular immune responses and inflammatory dysregulation are believed to play essential roles in disease progression and severity. Case Presentation: We present the first case of a patient with COVID-19 with massive pulmonary embolism treated successfully with systemic thrombolysis, VA-ECLS, and bail out catheter directed thrombolysis. He was discharged from the hospital after an eventful hospital course on therapeutic anticoagulation with warfarin. Conclusions: We present the first case of a patient with COVID-19 with massive pulmonary embolism (PE) treated successfully with systemic thrombolysis, VA-ECLS and bail out catheter directed thrombolysis. In our experience catheter directed thrombolysis comes with an acceptable bleeding risk despite use of mechanical circulatory support, particularly with meticulous attention to vascular access and dose response monitoring.
Databáze: Directory of Open Access Journals
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