The Triglyceride-Glucose Index is Independently Associated with Chronic Kidney Disease in the Geriatric Population, Regardless of Obesity and Sex
| Autor: | Bokun Kim, Gwon-Min Kim, Kihoon Han, Naoki Maki, Keisuke Taniguchi, Sechang Oh |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Annals of Geriatric Medicine and Research, Vol 27, Iss 3, Pp 258-265 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2508-4798 2508-4909 |
| DOI: | 10.4235/agmr.23.0096 |
| Popis: | Background Insulin resistance (IR) negatively affects several risk factors of chronic kidney disease (CKD). This cross-sectional study investigated whether the triglyceride-glucose (TyG) index, which reflects IR, was independently associated with CKD in a geriatric population, regardless of obesity and sex. Methods The analysis included 7,326 individuals (2,864 males and 4,462 females) aged ≥60 years. Non-obesity or obesity was evaluated using a body mass index cutoff of 25 kg/m2. The TyG index was calculated as ln [triglyceride concentration (mg/dL)×fasting plasma glucose concentration (mg/dL)]/2. All participants were categorized into three groups according to TyG tertiles. Moderate-to-severe CKD (MSCKD) was defined as an estimated glomerular filtration rate (eGFR) of |
| Databáze: | Directory of Open Access Journals |
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