PILOT STUDY ON ACID BURNS OF THE OESOPHAGUS IN GUINEA PIGS

Autor: Valentin K. Stojanov, Borislav D. Dimitrov
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Zdroj: Acta Medica Medianae, Vol 42, Iss 2, Pp 5-8 (2003)
Druh dokumentu: article
ISSN: 0365-4478
Popis: Correct time determination for beginning of the first bougienage in cases with Stomatoesophagitis corrosiva is probably the most important step for successful outcome of treatment procedures. The aim of this study was to describe patterns of acid burns of the oesophagus in Guinea pigs. We tested 20 animals (mean initial weight of 520 g on average) divided into two groups: Group 1 (subjected to 98% H2S04) and Group 2 (15% H2S04). Changes in weight, pathohistological findings (biopsy), time and cause of death (after International Classification of Diseases - 9th revision) were analysed. The results revealed that animals from Group 1 died about the day 6 from ingestion of the acid with mean decrease of weight of 9.83% as the difference with the initial one was statistically significant (p
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