Associated factors of REM sleep without atonia in younger (≤ 50 years) hospitalized psychiatric patients

Autor: Jitka Bušková, Eva Miletínová, Monika Kliková, Martin Bareš, Tomáš Novák, Jiřina Kosová, Pavla Stopková, Jana Kopřivová
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Psychiatry, Vol 20, Iss 1, Pp 1-8 (2020)
Druh dokumentu: article
ISSN: 1471-244X
DOI: 10.1186/s12888-020-02879-4
Popis: Abstract Background Isolated REM sleep without atonia (RSWA) as a main polysomnograhic feature of REM sleep behaviour disorder (RBD) is thought to be a prodromal or subclinical state of the disease. RSWA/RBD occurence in psychiatric population is much more frequent than in general population but its associated factors are still not known. Methods We invited 88 psychiatry in-patients to undervent video-polysomnography. The visual scoring was focused on RSWA in submentales and flexores digitales superficiales muscles. This parametr was subsequently correlated mainly with age/gender, their medication and mental status. Results The RWSA was mostly still in normal range despite the fact, that selected psychiatry patients (≤ 50 years) were taking several classes of psychoactive medication. 3,6% had convincingly RBD, although 35.7% reported rare lifetime occurence of dream-enacting behaviour and 62.8% sporadic nightmares. We found correlation between RSWA and SNRI medication class (p = 0.015), specifically venlafaxine (p = 0.029) as well as quetiapine (p = 0.030). Another significant associated factors were current anxiety (p
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