Practical experience of ustekinumab in patients with moderate-to-severe psoriasis who had inadequate therapeutic response to previous tumor necrosis factor blockers

Autor: Tzu-Chang Wang, Hsien-Yi Chiu, Ting-Shun Wang, Tsen-Fang Tsai
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Dermatologica Sinica, Vol 33, Iss 1, Pp 5-10 (2015)
Druh dokumentu: article
ISSN: 1027-8117
DOI: 10.1016/j.dsi.2014.09.005
Popis: Background/Objective(s): Few studies have evaluated the therapeutic response among switchers of biologics in patients with psoriasis. We report our experience of ustekinumab in patients with psoriasis who did not respond adequately to tumor necrosis factor (TNF) blockers treatment previously. Methods: We retrospectively reviewed the therapeutic response of 20 patients with moderate-to-severe psoriasis who had failed conventional treatment and had inadequate therapeutic response to previous etanercept and/or adalimumab between 2012 and 2013. Inadequate therapeutic response is defined by
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